wbi@bwh.harvard.edu
Bi Lab
MENINGIOMA REGISTRY
← Bi Lab
Adjacent (not core)

A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors (serum component)

10.6084/m9.figshare.26620783.v1, 10.6084/m9.figshare.26620789.v1Halder et al., 2023
View on Figshare ↗

Overview

Modality
Proteomics (bulk MS)
Sample count
51
Patient count
Not reported
Institution
Indian Institute of Technology (IIT) Bombay; serum provided by Tata Memorial Centre, Mumbai
Corresponding author
Sanjeeva Srivastava
Platform
TSQ Altis triple-quadrupole mass spectrometer (Thermo Fisher Scientific) coupled to a Dionex Ultimate 3000 HPLC; targeted MRM (multiple reaction monitoring) (same platform as the tissue component, per the paper's shared Methods section)
Access type
open
Tissue preservation
liquid_biopsy
WHO edition
2021

Cohort detail

Grade breakdown
G1: 17 G2: 14 G3: 0
Sex distribution
26 female / 19 male / 6 not recorded (n=51 total, all conditions combined; not separately tabulated for the meningioma-only subset)
Age distribution
Range 25-81 years (n=45 with age recorded, 6 missing; all conditions combined, not separately tabulated for the meningioma-only subset)
Anatomic location
Not reported
Brain invasion
Not reported
Normal/control tissue
healthy control serum (n=6), plus 14 glioblastoma (GBM) serum samples included as an inter-tumor comparison group (not meningioma) (n=6)

Priority attributes

WHO grade breakdown availablePeer-reviewed

Publications

  • Halder A, et al. A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors. Clinical Proteomics, 2023. PMID 37770851 · DOI

Related datasets

Also related: 10.6084/m9.figshare.24217443.v1

Sources

  • Figshare
    https://springernature.figshare.com/articles/dataset/Additional_file_3_of_A_large-scale_targeted_proteomics_of_serum_and_tissue_shows_the_utility_of_classifying_high_grade_and_low_grade_meningioma_tumors/26620783
  • Figshare
    https://springernature.figshare.com/articles/dataset/Additional_file_5_of_A_large-scale_targeted_proteomics_of_serum_and_tissue_shows_the_utility_of_classifying_high_grade_and_low_grade_meningioma_tumors/26620789
  • Figshare
    https://springernature.figshare.com/articles/dataset/Additional_file_1_of_A_large-scale_targeted_proteomics_of_serum_and_tissue_shows_the_utility_of_classifying_high_grade_and_low_grade_meningioma_tumors/24217443
  • pmc.ncbi.nlm.nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10540342/
  • PubMed
    https://pubmed.ncbi.nlm.nih.gov/37770851/
  • DOI
    https://doi.org/10.1186/s12014-023-09426-9