wbi@bwh.harvard.edu

A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors (tissue component)

10.6084/m9.figshare.24217661.v1, 10.6084/m9.figshare.26620792.v1Halder et al., 2023
Modality
Proteomics (bulk MS)
Sample count
53
Patient count
Not reported
Institution
Indian Institute of Technology (IIT) Bombay; tissue provided by Tata Memorial Centre, Mumbai
Corresponding author
Sanjeeva Srivastava
Platform
TSQ Altis triple-quadrupole mass spectrometer (Thermo Fisher Scientific) coupled to a Dionex Ultimate 3000 HPLC; targeted MRM (multiple reaction monitoring)
Access type
open
Tissue preservation
fresh_frozen
WHO edition
2021
Grade breakdown
G1: 23 G2: not reported G3: not reported
Sex distribution
Reported per-sample in Additional file 1's Tissue sheet (F/M), aggregate not separately tabulated for the meningioma-only subset
Age distribution
Reported per-sample in Additional file 1's Tissue sheet, aggregate not separately tabulated for the meningioma-only subset
Anatomic location
Not reported
Brain invasion
Not reported
Normal/control tissue
healthy control tissue (n=8), plus 4 glioma/glioblastoma tissue samples included as an inter-tumor comparison group (not meningioma) (n=8)
WHO grade breakdown availablePeer-reviewed
  • Halder A, et al. A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors. Clinical Proteomics, 2023. PMID 37770851 · DOI

Also related: 10.6084/m9.figshare.24217443.v1

Sources

  • Figshare
    https://springernature.figshare.com/articles/dataset/Additional_file_2_of_A_large-scale_targeted_proteomics_of_serum_and_tissue_shows_the_utility_of_classifying_high_grade_and_low_grade_meningioma_tumors/24217661
  • Figshare
    https://springernature.figshare.com/articles/dataset/Additional_file_6_of_A_large-scale_targeted_proteomics_of_serum_and_tissue_shows_the_utility_of_classifying_high_grade_and_low_grade_meningioma_tumors/26620792
  • Figshare
    https://springernature.figshare.com/articles/dataset/Additional_file_1_of_A_large-scale_targeted_proteomics_of_serum_and_tissue_shows_the_utility_of_classifying_high_grade_and_low_grade_meningioma_tumors/24217443
  • pmc.ncbi.nlm.nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10540342/
  • PubMed
    https://pubmed.ncbi.nlm.nih.gov/37770851/
  • DOI
    https://doi.org/10.1186/s12014-023-09426-9