Transcriptomic profiling of meningiomas reveals SMARCB1 mutation-driven immunosuppression via IL-17/CSF1 axis
GSE304666Jin et al., 2026
Overview
- Modality
- Bulk RNA-seq
- Sample count
- 14
- Patient count
- Not reported
- Institution
- The Affiliated Shanghai Fourth People's Hospital of Tongji University
- Corresponding author
- Juxiang Chen, Miaoxia He
- Platform
- Illumina NovaSeq 6000 (GPL24676)
- Access type
- open
- Tissue preservation
- ffpe
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- G1: 5 G2: 5 G3: 3
- Sex distribution
- Not reported
- Age distribution
- Not reported
- Anatomic location
- Not reported
- Brain invasion
- Not reported
- Normal/control tissue
- dura mater (n=1)
Priority attributes
WHO grade breakdown availablePrimary vs. recurrent annotatedPeer-reviewed
Publications
- Jin B, et al. Deficiency of SMARCB1 drives an immunosuppressive microenvironment in meningioma. Acta Neuropathologica Communications, 2026. PMID 41578352 · DOI
Sources
- GEOhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE304666