Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors
GSE136661Patel et al., 2019
Overview
- Modality
- Bulk RNA-seq
- Sample count
- 160
- Patient count
- 140
- Institution
- Baylor College of Medicine
- Corresponding author
- Ying-Wooi Wan, Huda Y. Zoghbi, Tiemo J. Klisch
- Platform
- Illumina HiSeq 4000 (GPL20301)
- Access type
- open
- Tissue preservation
- Not reported
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- G1: 121 G2: 32 G3: 7
- Sex distribution
- 93 female, 52 male, 15 not determined (n=160, from GSM 'gender' field)
- Age distribution
- n=160, range 18-81, mean 58.9 (from GSM 'age' field)
- Anatomic location
- Not reported
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
WHO grade breakdown availableLarge cohort (top quartile)Molecular subtype annotatedOutcome/survival dataPeer-reviewed
Publications
- Patel AJ, et al. Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors. Proceedings of the National Academy of Sciences of the United States of America, 2019. PMID 31591222 · DOI