Proteomic Analysis Identifies ATE1-Dependent Arginylation Dysregulation across Meningioma Grades
10.1021/acs.jproteome.5c01173.s004, 10.1021/acs.jproteome.5c01173.s003Macedo-da-Silva et al., 2026
Overview
- Modality
- Proteomics (bulk MS)
- Sample count
- 12
- Patient count
- 13
- Institution
- University of São Paulo (USP), GlycoProteomics Laboratory (Dept. of Parasitology, ICB) / Faculdade de Medicina FMUSP
- Corresponding author
- Giuseppe Palmisano
- Platform
- Not reported (proteinGroups.txt is a MaxQuant search-result export; instrument model not stated in the supplementary file itself)
- Access type
- open
- Tissue preservation
- Not reported
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- G1: 7 G2: 5 G3: not reported
- Sex distribution
- 13 clinical cases: 8 female, 5 male (Table 1 of supplementary clinical file); sex not separately reported for the 12-sample proteomics subset
- Age distribution
- 13 clinical cases range 33-72 years (Table 1 of supplementary clinical file)
- Anatomic location
- 11 of 13 clinical cases convexity, 2 of 13 skull base (SB), per Table 1 of the supplementary clinical annotation file
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
WHO grade breakdown availablePrimary vs. recurrent annotatedMolecular subtype annotatedOutcome/survival dataPeer-reviewed
Publications
- Macedo-da-Silva J, et al. Proteomic Analysis Identifies ATE1-Dependent Arginylation Dysregulation across Meningioma Grades. Journal of Proteome Research, 2026. PMID 42372081 · DOI
Sources
- Figsharehttps://acs.figshare.com/articles/dataset/Proteomic_Analysis_Identifies_ATE1-Dependent_Arginylation_Dysregulation_across_Meningioma_Grades/32829844
- Figsharehttps://acs.figshare.com/articles/dataset/Proteomic_Analysis_Identifies_ATE1-Dependent_Arginylation_Dysregulation_across_Meningioma_Grades/32829841
- Figsharehttps://acs.figshare.com/articles/dataset/Proteomic_Analysis_Identifies_ATE1-Dependent_Arginylation_Dysregulation_across_Meningioma_Grades/32829844
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/42372081/
- DOIhttps://doi.org/10.1021/acs.jproteome.5c01173